Achievement

Original Article

2010年

■ピンクの網掛けは教室が中心して行った業績

  1. Komiya, K., Uchida, T., Ueno, T., Koike, M., Abe, H., Hirose, T., Kawamori, R., Uchiyama, Y., Kominami, E., Fujitani, Y., Watada, H. Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. Biochem. Biophys. Res. Commun. 401(4): 561-7; 2010.
    doi: 10.1016/j.bbrc.2010.09.101
  2. Kaneko, N., Marin, O., Koike, M., Hirota, Y., Uchiyama, Y., Wu, J.Y., Lu, Q., Tessier-Levigne, M., Alvarez-Buylla, A., Okano, H., Rubenstein, J.L., Sawamoto, K. New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron 67(2): 213-23; 2010.
    doi: 10.1016/j.neuron.2010.06.018
  3. Sasaki, K., Hamasaki, J., Koike, M., Hirano, Y., Komatsu, M., Uchiyama, Y., Tanaka, K., Murata, S. PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol. Cell Biol. 30(15): 3864-74; 2010.
    doi: 10.1128/MCB.00216-10
  4. Hadano, S., Otomo, A., Kunita, R., Suzuki-Utsunomiya, K., Akatsuka, A., Koike, M., Aoki, M., Uchiyama, Y., Itoyama, Y., Ikeda, J.E. Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking. PLoS ONE 5(3): e9805; 2010.
    doi: 10.1371/journal.pone.0009805
  5. Shimada, N., Ohno-Matsui, K., Iseki, S., Koike, M., Uchiyama, Y., Wang, J., Yoshida, T., Sato, T., Peters, C., Mochizuki, M., Morita, I. Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization. Am. J. Pathol. 176(5): 2571-80; 2010.
    doi: 10.2353/ajpath.2010.091027
  6. Shibata, M., Yoshimura, K., Tamura, H., Ueno, T., Nishimura, T., Inoue, T., Sasaki, M., Koike, M., Arai, H., Kominami, E., Uchiyama, Y. LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biochem. Biophys. Res. Commun. 393(2): 274-9; 2010.
    doi: 10.1016/j.bbrc.2010.01.121
  7. Tamura, H., Shibata, M., Koike, M., Sasaki, M., Uchiyama, Y. Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains. J. Histochem. Cytochem. 58(5): 443-53; 2010.
    doi: 10.1369/jhc.2010.955690
  8. Matsuda, T., Kido, Y., Asahara, S., Kaisho, T., Tanaka, T., Hashimoto, N., Shigeyama, Y., Takeda, A., Inoue, T., Shibutani, Y., Koyanagi, M., Hosooka, T., Matsumoto, M., Inoue, H., Uchida, T., Koike, M., Uchiyama, Y., Akira, S., Kasuga, M. Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice. J. Clin. Invest. 120(1): 115-26; 2010.
    doi: 10.1172/JCI39721