業 績Achievement
2013年
■ピンクの網掛けは教室が中心して行った業績
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Nonomura, K., Yamaguchi, Y., Hamachi, M., Koike, M., Uchiyama, Y., Nakazato, K., Mochizuki, A., Sakaue-Sawano, A., Miyawaki, A., Yoshida, H., Kuida, K., Miura, M. Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells. Dev. Cell 27(6):621-634, 2013.
doi: 10.1016/j.devcel.2013.11.015
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Abe, H., Uchida, T., Hara, A., Mizukami, H., Komiya, K., Koike, M., Shigihara, N., Toyofuku, Y., Ogihara, T., Uchiyama, Y., Yagihashi, S., Fujitani, Y., Watada, H. Exendin-4 improves beta cell function in autophagy-deficient beta cells. Endocrinology 154(12):4512-24, 2013.
doi: 10.1210/en.2013-1578
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Okura, H., Kobayashi, T., Koike, M., Ohsawa, M., Zhang, D., Arai, H., Uchiyama, Y., Hino, O. Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway. Int. J. Oncol. 43(2):447-56, 2013.
doi: 10.3892/ijo.2013.1984
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Koike, M.*, Tanida, I.*, Nanao, T., Tada, N., Iwata, J., Ueno, T., Kominami, E., Uchiyama, Y. Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons. PLoS ONE 8(5):e63568, 2013. (*These authors contributed equally to this work)
doi: 10.1371/journal.pone.0063568
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Matsui, H.*, Sato, F.*, Sato, S., Koike, M., Taruno, Y., Saiki, S., Funayama, M., Ito, H., Taniguchi, Y., Uemura, N., Toyoda, A., Sakaki, Y., Takeda, S., Uchiyama, Y., Hattori, N., Takahashi, R. ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons. FEBS Lett. 587(9):1316-25, 2013. (*These authors contributed equally to this work)
doi: 10.1016/j.febslet.2013.02.046
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Ohkouchi, S., Shibata, M., Sasaki, M., Koike, M., Saftig, P., Peters, C., Nagata, S., Uchiyama, Y. Biogenesis and proteolytic processing of lysosomal DNase II. PLoS ONE 8(3):e59148, 2013.
doi: 10.1371/journal.pone.0059148
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Koike, M., Shibata, M., Ezaki, J., Peters, C., Saftig, P., Kominami, E., Uchiyama, Y. Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system. Eur. J. Neurosci. 37(5):816-30, 2013.
doi: 10.1111/ejn.12096
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Hayakawa, N., Shiozaki, M., Shibata, M., Koike, M., Uchiyama, Y., Matsuura, N., Gotow, T. Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions. Eur. J. Cell Biol. 92(1):30-43, 2013.
doi: 10.1016/j.ejcb.2012.10.002