Achievement

Original Article

2016年

■ピンクの網掛けは教室が中心して行った業績

  1. Tsuboyama, K.*, Koyama-Honda, I.*, Sakamaki, Y., Koike, M., Morishita, H., Mizushima, N. The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. Science 354(6315):1036-41, 2016. (*These authors contributed equally to this work)
    doi: 10.1679/aohc.77.13
  2. Yamanaka, T., Tosaki, A., Miyazaki, H., Kurosawa, M., Koike, M., Uchiyama, Y., Maity, SN., Misawa, H., Takahashi, R., Shimogori, T., Hattori, N., Nukina, N. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci. Rep. 6:34575, 2016.
    doi: 10.1038/srep34575
  3. Sato, S., Koike, M., Funayama, M., Ezaki, J., Fukuda, T., Ueno, T., Uchiyama, Y., Hattori, N. Lysosomal storage of subunit c of mitochondrial ATP synthase in brain-specific ATP13a2-deficient mice. Am. J. Pathol. 186(12):3074-82, 2016.
    doi: 10.1016/j.ajpath.2016.08.006
  4. Hadano, S., Mitsui, S., Pan, L., Otomo, A., Kubo, M., Sato, K., Ono, S., Onodera, W., Abe, K., Koike, M., Uchiyama, Y., Aoki, M., Warabi, E., Yamamoto, M., Ishii, T., Yanagawa, T., Shang, HF., Yoshii, F. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: Cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice. Hum. Mol. Genet. 25(15):3321-40, 2016.
    doi: 10.1093/hmg/ddw180
  5. Sunabori, T., Koike, M., Asari, A., Oonuki, Y., Uchiyama, Y. Suppression of ischemia-induced hippocampal pyramidal neuron death by hyaluronan tetrasaccharide through inhibition of Toll-like receptor 2 signaling pathway. Am. J. Pathol. 186(8):2143-51, 2016.
    doi: 10.1016/j.ajpath.2016.03.016
  6. Morales, J., Hashimoto, M., Williams, T., Hirawake-Mogi, H., Makiuchi, T., Tsubouchi, A., Kaga, N., Taka, H., Fujimura, T., Mita, T., Koike, M., Bringaud, F., Concepción, J., Hashimoto, T., Embley, M., Nara, T. Differential remodelling of peroxisome function underpins the environmental and metabolic adaptability of diplonemids and kinetoplastids. Proc Biol Sci. 283(1830), 2016.
    doi: 10.1098/rspb.2016.0520
  7. Shibata, M., Koike, M., Kusumi, S., Sato, N., Uchiyama, Y. A specific tripeptidyl substrate for tripeptidyl peptidase activity is effectively hydrolyzed by alanyl aminopeptidase/aminopeptidase N/CD13 in the rat kidney. Arch Histol Cytol. 76(1):1-8, 2016.
    doi: 10.1679/aohc.76.1
  8. Sekine S.*, Yao, A.*, Hattori, K., Sugawara, S., Naguro, I., Koike, M., Uchiyama, Y., Takeda, K., Ichijo, H. PGAM5 deficiency confers resistance against metabolic stress in mice. EBioMedicine 5:82-92, 2016. (*These authors contributed equally to this work)
    doi: 10.1016/j.ebiom.2016.01.031
  9. Yamada, D., Saiki, S., Furuya, N., Ishikawa, K., Imamichi, Y., Kambe, T., Fujimura, T., Ueno, T., Koike, M., Hattori, N. Ethambutol neutralizes lysosomes and causes lysosomal zinc accumulation. Biochem. Biophys. Res. Commun. 471(1):109-16, 2016.
    doi: 10.1016/j.bbrc.2016.01.171
  10. Yamamoto-Nonaka K., Koike, M., Asanuma, K., Akiba-Takagi, M., Trejo, JA., Seki, T., Hidaka, T., Ichimura, K., Sakai, T., Tada, N., Ueno, T., Uchiyama, Y., Tomino, Y. Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD. J. Am. Soc. Nephrol. 27(9):2685-700, 2016.
    doi: 10.1681/ASN.2015040366
  11. Xie, C., Ginet, V., Sun, Y., Koike, M., Zhou, K., Li, T., Li, H., Li, Q., Wang, X., Uchiyama, Y., Truttmann, AC., Kroemer, G., Puyal, J., Blomgren, K., Zhu, C. Neuroprotection by selective neuronal deletion of autophagy-related gene ATG7 in neonatal brain injury. Autophagy 12(2):410-23, 2016
    doi: 10.1080/15548627.2015.1132134