業 績Achievement
2018年
■ピンクの網掛けは教室が中心して行った業績
-
Komine, O., Yamashita, H., Fujimori-Tonou, N., Koike, M., Jin, S., Moriwaki, Y., Endo, F., Watanabe, S., Uematsu, S., Akira, S., Uchiyama, Y., Takahashi, R., Misawa, H., Yamanaka, K. Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Cell Death Differ. 25(12):2130-46, 2018.
doi: 10.1038/s41418-018-0098-3
-
Eguchi, T., Kuwabara, T., Sakurai, M., Komori, T., Fujimoto, T., Ito, G., Yoshimura, S., Harada, A., Fukuda, M., Koike, M., Iwatsubo, T. LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis. Proc. Natl. Acad. Sci. USA 115(39):E9115-E9124, 2018.
doi: 10.1073/pnas.1812196115
-
Osonoi, Y., Mita, T., Azuma, K., Nakajima, K., Matsuyama, A., Goto, H., Nishida, Y., Miyatsuka, T., Fujitani, Y., Koike, M., Mitsumata, M., Watada, H. Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. Autophagy 14(11):1991-2006, 2018.
doi: 10.1080/15548627.2018.1501132
-
Shimada, Y., Shimura, H., Tanaka, R., Yamashiro, K., Koike, M., Uchiyama, Y., Urabe, T., Hattori, N. Phosphorylated recombinant HSP27 protects the brain and attenuates blood-brain barrier disruption following stroke in mice receiving intravenous tissue-plasminogen activator. PLoS ONE 13(5):e0198039, 2018
doi: 10.1371/journal.pone.0198039
-
Ogawa, M., Matsuda, R., Takada, N., Tomokiyo, M., Yamamoto, S., Shizukuishi, S., Yamaji, T., Yoshikawa, Y., Yoshida, M., Tanida, I., Koike, M., Murai, M., Morita, H., Takeyama, H., Ryo, A., Guan, JL., Yamamoto, M., Inoue, J., Yanagawa, T., Fukuda, M., Kawabe, H., Ohnishi, M. Mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1 mediated K63-linked ubiquitination. Cell Microbiol. 20(8):e12846, 2018.
doi: 10.1111/cmi.1284610.1111/cmi.12846
-
Tanida-Miyake, E., Koike, M., Uchiyama, Y., Tanida, I. Optimization of mNeonGreen for Homo sapiens increases its fluorescent intensity in mammalian cells. PLoS ONE 13(1):e0191108, 2018.
doi: 10.1371/journal.pone.0191108