業 績Achievement
2023年
■ピンクの網掛けは教室が中心して行った業績
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Murakami, Y., Umeshita, S., Imanishi, K., Yoshioka, Y., Ninomiya, A., Sunabori, T., Likhite S., Koike, M., Mayer KC., Kinoshita, T. AAV-based gene therapy ameliorated central nervous system specific GPI defect in mouse models. Mol. Ther. Methods Clin. Dev. 32(1):101176, 2023.
doi: 10.1016/j.omtm.2023.101176
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Uemura, N., Marotta, N., Ara, Y., Meymand, E., Zhang, B., Kameda, H., Koike, M., Luk, K., Trojanowski, J., Lee, V. alpha-Synuclein aggregates amplified from patient-derived Lewy bodies recapitulate pathological features of Lewy body diseases in mice. Nat. Commun. 14(1):6892, 2023.
doi: 10.1038/s41467-023-42705-5
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Yokota, M. *, Yoshino, Y. *, Hosoi, M., Hashimoto, R., Kakuta, S., Shiga, T., Ishikawa K., Okano, H., Hattori, N., Akamatsu W., Koike, M. Reduced ER-mitochondrial contact sites and mitochondrial Ca2+ flux in PRKN-mutated patient tyrosine hydroxylase reporter iPSC lines. Front. Cell Dev. Biol. 11:1171440, 2023. (*These authors contributed equally to this work)
doi: 10.3389/fcell.2023.1171440
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Kanai, A., Nishida, Y., Iwamoto, T., Yokota, M., Aoyama, S., Ueki, K., Ito, M., Uzawa, H., Iida, H., Koike, M., Watada, H. Genome-wide screening for regulators of degradation of insulin secretory granules with a fluorescent reporter. Biochem. Biophys. Res. Commun. 676:132-140, 2023.
doi: 10.1016/j.bbrc.2023.07.040
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Silvia, L., Kato, Y., Wu YM., Yokota, M., Koike, M., Yui, S., Tsuchiya, K., Shiraki, N., Kume, S. The effect of Vitamin D3 and Valproic Acid on the maturation of human induced pluripotent stem cell-derived enterocyte-like cells. Stem Cells 41(8):775-91, 2023.
doi: 10.1093/stmcls/sxad042
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Kurusu, R.*, Fujimoto, Y.*, Morishita, H. *, Noshiro, D., Takada, S., Yamano, K., Tanaka, H., Arai, R., Kageyama, S., Funakoshi, T., Komatsu-Hirota, S., Taka, H., Kazuno, S., Miura, Y., Koike, M., Wakai, T., Waguri, S., Noda, N., Komatsu, M. Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex. Dev. Cell 58(13):1189-1205, 2023.(*These authors contributed equally to this work)
doi: 10.1016/j.devcel.2023.04.015
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Okamoto, K., Kamikubo, Y., Yamauchi, K., Okamoto, S., Takahashi, M., Ishida, Y., Koike, M., Ikegaya, Y., Sakurai, T., Hioki, H. Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle. Sci. Rep. 13(1):323, 2023.
doi: 10.1038/s41598-022-27372-8
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Takahashi, M., Kobayashi, T., Mizuma, H., Yamauchi, K., Okamoto S., Okamoto, K., Ishida, Y., Koike, M., Watanabe M., Isa, T., Hioki, H. Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum. Neurosci. Res. 190:92-106, 2023
doi: 10.1016/j.neures.2022.11.008