業 績Achievement
2014年
■ピンクの網掛けは教室が中心して行った業績
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Suyama, M.*, Koike, M.*, Asaoka, D., Mori, H., Oguro, M., Ueno, T., Nagahara, A., Watanabe, S. Uchiyama, Y. Increased immunoreactivity of cathepsins in the rat esophagus under chronic acid reflux esophagitis. J. Histochem. Cytochem. 62(9):645-60, 2014. (*These authors contributed equally to this work)
doi: 10.1369/0022155414542300
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Ueshima S., Nishida, T., Koike, M., Matsuda, H., Sawa, Y., Uchiyama, Y. Nitric oxide-mediated injury of interstitial cells of Cajal and intestinal motility under endotoxemia of mice. Biomed. Res. 35(4):251-62, 2014.
doi: 10.2220/biomedres.35.251
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Shigihara, N.*, Fukunaka, A.*, Hara, A.*, Komiya, K., Honda, A., Uchida, T., Abe, H., Toyofuku, Y., Tamaki, M., Ogihara, T., Miyatsuka, T., Hiddinga, HJ, Sakagashira. S., Koike, M., Uchiyama, Y., Yoshimori, T., Eberhardt, NL, Fujitani, Y.*, Watada, H. Human IAPP-induced pancreatic beta-cell toxicity and its regulation by autophagy. J. Clin. Invest. 124(8):3634-44, 2014. (*These authors contributed equally to this work)
doi: 10.1172/JCI69866
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Bartolomé, A., Kimura-Koyanagi, M., Asahara, S., Guillén, C., Teruyama, K., Inoue, H., Shimizu, S., Kanno, A., García-Aguilar, A., Koike, M., Uchiyama, Y., Benito, M., Noda, T., Kido, Y. Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic impairment. Diabetes 63(9):2996-3008, 2014.
doi: 10.2337/db13-0970
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Ishikawa, K., Saiki, S., Furuya, N., Yamada, D., Imaichi, Y., Li, Y., Kawajiri, S., Sasaki, H., Koike, M., Tsuboi, Y., Hattori N. p150glued-associated disorders are caused by activation of intrinsic apoptotic pathway. Plos ONE 9(4):e94645, 2014.
doi: 10.1371/journal.pone.0094645
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Yamanaka, T., Tosaki, A., Kurosawa, M., Matsumoto, G., Koike, M., Uchiyama, Y., Maity, S.N., Hattori, N., Nukina, N. Neuronal NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin/p62 accumulation and endoplasmic reticulum disorganization. Nat. Commun. 5:3354, 2014.
doi: 10.1038/ncomms4354
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Awazawa, M., Futami, T., Kaneko, K., Osugi, M., Nakaya, K., Terai, I., Suzuki, R., Koike, M., Uchiyama, Y., Kadowaki, T., Ueki, K. Deregulation of pancreas-specific oxidoreductin ERO1β in the pathogenesis diabetes mellitus. Mol. Cell Biol. 34(7):1290-9, 2014.
doi: 10.1128/MCB.01647-13